Welcome to the Xing Laboratory of RNA Genomics and Bioinformatics!

We are in the Department of Internal Medicine and Department of Biomedical Engineering at University of Iowa. We are also affliated with the Ph.D. programs in Genetics, Biosciences, Biostatistics, and Informatics.

Current Research Topics:

Our laboratory uses genomic, computational and molecular approaches to study gene expression and RNA processing in mammalian genomes. We develop computational and statistical tools for exon-level analysis of mammalian transcriptomes using high-density exon microarray and ultra-deep RNA-sequencing data. We conduct computational and experimental research to elucidate the molecular mechanism and regulatory impact of evolutionary changes in gene expression and RNA processing. We are also studying the role of alternative splicing and microRNAs in human diseases.